Mediation of Transforming Growth Factor-β1-Stimulated Matrix Contraction by Fibroblasts
نویسندگان
چکیده
منابع مشابه
Transforming growth factor-β1-mediated collagen gel contraction by cardiac fibroblasts
Results TGF-β1 dose-dependently increased the contraction of collagen gel mediated by cardiac fibroblasts, reaching a maximal effect at 100 pmol/L TGF-β1. TGF-β1 also stimulated H-thymidine incorporation and total protein content in cardiac fibroblasts in the collagen gel lattice. TGF-β1 dose-dependently induced an increase in αsmooth muscle actin, a marker of myofibroblasts. The TGF-β1-induced...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2003
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)63562-6